One of the greatest challenges that we face in discovering new disease therapies is that most proteins are considered “undruggable.” Our research group is reimagining druggability by using chemoproteomic approaches to tackle the undruggable proteome.
Meet Our Team
We are a group of highly motivated scientists with a desire to engage in multidisciplinary research at the interface of chemistry and biology.
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Congrats to Mai Luo for starting his position as an Assistant Professor at China Agricultural University
Congrats to Mai Luo and Jessica Spradlin for their Cell Chemical Biology paper on a fully synthetic RNF114 ligand for targeted protein degradation applications!
Congrats to Jessica Spradlin for graduating with her PhD from our lab and the chemistry/chemical biology program!
Our work on SARS-CoV-2 and our recent MYC inhibitor story highlighted by Mark Foundation for Cancer Research
Happy to showcase our new paper with the Maimone lab and Novartis on Keap1/Nrf2 activator Bardoxolone as a new E3 ligase recruiter for targeted protein degradation applications now out in Scientific Reports! Congrats to grad student Bingqi Tong and postdoc Mai Luo!!
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