Nomura Research Group

Research

Our Team

Publications

The structure of the SALL4-Pomalidomide-Cereblon-DDB1 complex provides insights for rational design of cereblon binding drug…

Work from @FloydRomesberg’s group described the first semi-synthetic organism with 67 codons. nature.com/articles/s4158…

Work from Nathanael Gray, @FleurMFerguson and @behnamnabet identified a highly selective inhibitor of the DCLK1/2 kinases to…

Behnam Nabet @behnamnabet

Thrilled to share our advances towards targeting DCLK1 in pancreatic cancer, now out in @nchembio. We present a highly sel…

Stephan Hacker @StephanHacker2

New post by @DennisWhom on drug-hunter.com. Molecules of the Month March. Great to see at least four covalent i…

Jen Heemstra @jenheemstra

New data on chloroquine + azithromycin for treating #COVID19 don’t look so encouraging. 8/10 patients still positive after…

Ingo Hartung @HartungIngo

Awesome PK-PD-study by @GSK with RIPK2 #PROTACs: Affinity & property (logD, solubility, stability) based optimization allo…

Stephan Hacker @StephanHacker2

New paper by the group of Thomas Dick @ThomasD57648102 in @NatureComms. Pyrazinamide leads to the degradation of its ta…

Dan Nomura @DanNomura

Another latest preprint ⁦@biorxivpreprint⁩ w/ #Maimonelab & ⁦@NovartisScience⁩ showing nimbolide-based kinase degra… twitter.com/i/web/status/1…

Chemo- Proteomics

Chemical Biology

Drug Discovery

Nomura

Covalent Ligand Discovery

Natural Product Target Discovery

Induced Proximity Modalities

Nomura

Reimagining Druggability using Chemoproteomic Platforms