Congrats to Ethan Toriki and James Papaztimas on their discovery of rational chemical design strategies for molecular glue degraders

We posted our BioRxiv preprint on our discovery of a covalent fumarate-based chemical handle that targets RNF126 that can be transplanted onto a broad range of protein-targeting ligands to induce the degradation of their targets. BioRxiv link can be found here: https://www.biorxiv.org/content/10.1101/2022.11.04.512693v1