News

— NEWS

Congrats to chemical biology graduate student Jessica Spradlin for being awarded the NCI F99/K00 Predoctoral to Postdoctoral Transition Award!!

Jessica was previously an NCI F31 predoctoral fellowship recipient. The NCI Predoctoral to Postdoctoral Fellow Transition (F99/K00) Award supports outstanding Ph.D. and other Research Doctoral candidates complete…
— NEWS

Our new discovery by postdoc Mai Luo and grad student Jessica Spradlin on a fully synthetic covalent E3 ligase RNF114 recruiter for targeted protein degradation applications on BioRxiv!

You can read the paper here at: https://www.biorxiv.org/content/10.1101/2020.07.12.198150v1
— NEWS

Our paper by co-first author graduate students Bingqi Tong and Jessica Spradlin in collaboration with the Maimone lab on a nimbolide-based kinase degrader that preferentially degrades oncogenic BCR-ABL over c-ABL in ACS Chemical Biology!!

You can read the paper here: https://pubs.acs.org/doi/10.1021/acschembio.0c00348#.XvIP36QXlro.twitter
— NEWS

Our newest work by postdoc Yosuke Isobe in collaboration with the Maimone lab on a multi-covalent natural product “superglue” asukamycin that glues together UBR7 and TP53 to activate p53 and impair cancer cell proliferation!

You can read the paper here: https://www.nature.com/articles/s41589-020-0557-2
— NEWS

Congrats to chemical biology graduate student Lydia Boike for getting the NSF graduate fellowship and for passing her qualifying exam!!

Lydia is a second year graduate student in Chemistry/Chemical Biology and has been working on drugging undruggable transcription factors that drive cancer.