Congrats to Nafsika Forte for her paper on covalent recruitment of E2’s for targeted protein degradation

12/20/2022 — NEWS

Congrats to Nafsika Forte for her paper on covalent recruitment of E2’s for targeted protein degradation

In our latest BioRxiv preprint we discover a covalent recruiter against the E2 ubiquitin conjugating enzymes UBE2D which we use to degrade BRD4 and androgen receptor in cancer cells! https://www.biorxiv.org/content/10.1101/2022.12.19.520812v1